Oslo Mortality Study
Although contemporaneous effects of both individual (composition) and environment (context) on health have been demonstrated, we do not yet have a full understanding as to how the effect of context at different stages of the life course may influence subsequent health outcomes. We are conducting a series of studies to improve our understanding of this subject, in collaboration with Dr Øyvind Næss from the Norwegian Institute of Public Health in Oslo, based on the Oslo mortality study (a cohort of all inhabitants in Oslo aged 30 - 69 years in 1990, linked to the Censuses and various registers from 1960 - 1990, and to the death register from 1990-1998).
Næss Ø, Leyland AH. Analysing the effect of area of residence over the life course in multilevel epidemiology. Scandinavian Journal of Public Health 2010;38:119-26pubmed open access
Leyland AH, Næss Ø. The effect of area of residence over the life course on subsequent mortality. Journal of the Royal Statistical Society Series A 2009;172:555-78.open access
Næss Ø, Smith DG, Claussen B, Leyland AH. Life course influence of residential area on cause specific mortality. Journal of Epidemiology & Community Health 2008;62:29-34pubmed open access
Næss Ø, Piro F N, Nafstad P, Smith DG, Leyland AH. Air pollution, social deprivation, and mortality: a multilevel cohort study. Epidemiology 2007;18:686-694pubmed open access
Leyland AH. Assessing the impact of mobility on health: implications for life course epidemiology. Journal of Epidemiology & Community Health 2005;59:90-91pubmed
Næss Ø, Leyland AH , Davey-Smith G, Claussen B. Contextual effect on mortality of neighbourhood level education explained by earlier life deprivation. Journal of Epidemiology & Community Health 2005;59:1058-59pubmed
- cardiovascular disease Those diseases that affect the heart or blood vessels
- confounding A confounder or confounding variable is one which is related to an outcome and to an explanatory variable in a regression model but which is omitted from the analysis. The presence of a confounder may lead to an incorrect conclusion regarding the influence of one variable on another
- Contextual effects The effects of variables defined at a higher level (e.g. at an area level) on outcomes defined at a lower (e.g. individual) level.
- Induction time Time between exposure and the onset of disease.
- Life course In the context of life course epidemiology, this approach focuses on the stage of life that exposure to health promoting or harmful influences occurs and the duration of exposure to these influences
- Morbidity The state of being diseased.